Nicergoline

Description

CAS: 27848-84-6 | C24H26BrN3O3 | 484.394 g/mol

Nicergoline is an ergot derivative and vasodilator which increases blood flow in the brain. Nicergoline inhibits the vasoconstrictor effect of catecholamines by inhibiting the postsynaptic α1-adrenoceptors on vascular smooth muscle.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in alcohol, chloroform, and acetone. Insoluble in water.

Notes
Protect from heat. Store away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 27848-84-6
• Molecular Formula: C24H26BrN3O3
• Molecular Weight (g/mol): 484.394
• MDL Number: MFCD00869626
• InChI Key: YSEXMKHXIOCEJA-FVFQAYNVSA-N
• Synonym: nicergoline, nicotergoline, nimergoline, nimergoline base, nicergolinum, nicergolin, nicergolina, sermion, nicergolin german, nicergolina dcit
• PubChem CID: 34040
• IUPAC Name: [(6aR,9R,10aS)-10a-methoxy-4,7-dimethyl-6a,8,9,10-tetrahydro-6H-indolo[4,3-fg]quinoline-9-yl]methyl 5-bromopyridine-3-carboxylate
• SMILES: CN1CC(CC2(C1CC3=CN(C4=CC=CC2=C34)C)OC)COC(=O)C5=CC(=CN=C5)Br

• Color: White
• Quantity: 100 mg
• Merck Index: 14,6496
• Solubility Information: Soluble in alcohol,chloroform,and acetone. Insoluble in water.
• Formula Weight: 484.39
• Physical Form: Powder
• Chemical Name or Material: Nicergoline

Safety and Handling

Hazard Category	H302
Hazard Statement	GHS H Statement H302 Harmful if swallowed.
Precautionary Statement	P264b-P270-P301+P312-P330-P501c
EINECSNumber	248-694-6
RTECSNumber	KE6341000
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only