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Medchemexpress LLC Niclosamide olamine | 1420-04-8 | 98.7% | 1 ML
Supplier: Medchemexpress LLC HYB0497C10MM/1ML
Niclosamide olamine is an orally active antihelminthic agent primarily used in parasitic infection research. It functions as a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells. This compound also demonstrates biological activities against various cancers and inhibits DNA replication in Vero E6 cells.
- Orally active antihelminthic agent
- Used in parasitic infection research
- STAT3 inhibitor (IC50 of 0.25 μM in HeLa cells)
- Exhibits biological activities against cancer
- Inhibits DNA replication in Vero E6 cells
- Suppresses adrenocortical carcinoma cellular proliferation
- Reduces cyclin D1 and vimentin protein expression in human endometrial cancer cells
- Inhibits metabolic viability of AN3CA, Hec1B, and Ishikawa cells
- Suppresses colony formation in endometrial cancer cells
- Inhibits invasive properties of endometrial cancer cells
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