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Apexbio Technology LLC Nifuroxazide 965-52-6 200mg
Supplier: Apexbio Technology LLC B1799200
Nifuroxazide (CAS 965-52-6) is a small-molecule inhibitor targeting signal transducer and activator of transcription (STAT) signaling pathways It is designed to inhibit activation of STAT1 STAT3 and STAT5 thereby suppressing cytokine-mediated transcriptional activities Nifuroxazide exerts its biological activity primarily through inhibition of STAT phosphorylation and activation In cell-based assays Nifuroxazide demonstrates inhibitory activity with an IC50 value of approximately 3 M against STAT3 phosphorylation and activation in IL-6-stimulated U3A cells Based on these pharmacological properties Nifuroxazide holds research potential in studies of STAT-driven signaling processes and in exploring therapeutic strategies for diseases associated with aberrant cytokine signaling and STAT pathway activation
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