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Apexbio Technology LLC Nigericin sodium salt, 10mg CAS# 28643-80-3
Supplier: Apexbio Technology LLC B764410
Nigericin sodium salt is an ionophore that exchanges K+ for H+ across biological membranes.Ionophore is a lipid-soluble molecule that transports ions across the cell membrane.In medium with Na+, nigericin scarcely affected ADP-induced platelets aggregation, and slightly inhibited thrombin-induced platelets aggregation. Also, nigericin decreased the cytoplasmic pH in the medium with Na+. The effects of nigericin on platelet aggregation are mainly due to its effects on the cytoplasmic pH [1]. The K+ ionophore nigericin is highly effective as an ionophore for Pb2+. Physiological concentrations of Ca2+ or Mg2+ didnt inhibit nigericin-catalyzed Pb2+ transport, while K+ and Na+ concentrations (0-100 mM) modestly affected Pb2+ transport. Nigericin may be helpful in the treatment of Pb intoxication. Other sizes are also available. Please inqury us for quote.
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