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Medchemexpress LLC Nigericin sodium salt | 28643-80-3 | MFCD30377206 | 99.4% | 746.94 g/mol | C40H67NaO11 | 50 MG
Supplier: Medchemexpress LLC HY10038150MG
Nigericin sodium salt is an ionophore antibiotic used as an NLRP3 inflammasome activator in cell biology and pharmacology research. It facilitates transmembrane K+/H+ exchange to alter intracellular pH and is commonly used to trigger inflammasome activation, investigate ion transport, and study apoptosis and cancer-related signaling. Supplied as a solid with documented solubility and storage guidance for experimental use.
- Activates the NLRP3 inflammasome in cell-based assays.
- Acts as an ionophore facilitating K+/H+ exchange across membranes.
- Enables modulation of intracellular pH for mechanistic studies.
- Compatible with in vitro and in vivo formulation protocols provided by the supplier.
- Provided as a white to off-white solid with high analytical purity.
- Stable when stored under recommended sealed, low-temperature conditions.
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