Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Nikkomycin Z | 59456-70-1 | 98.6% | 495.44 | 1 MG
Supplier: Medchemexpress LLC HY195931MG
Nikkomycin Z is an orally active nucleoside peptide antifungal agent. It functions by inhibiting chitin synthesis, acting as a competitive analogue of the chitin synthase substrate UDP-N-acetylglucosamine. This compound demonstrates antifungal activity and enhances efficacy when combined with echinocandins such as Caspofungin and Micafungin. In vivo studies show it reduces fungal burden and extends survival in murine models of *Histoplasma capsulatum* infection.
- Inhibits chitin synthesis
- Competitive analogue of UDP-N-acetylglucosamine
- Active against *Candida albicans* and *Candida parapsilosis*
- Enhances efficacy with echinocandins
- Reduces fungal burden in *Histoplasma capsulatum* infection models
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?