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Cayman Chemical NIlvadIpIn 100mg
Supplier: Cayman Chemical 21243100 MG
An L-type calcium channel blocker; selective for L-type over N-, P/Q-, and R-type calcium channels at 10 μM; inhibits increases in systolic blood pressure induced by chronic intravenous infusion of endothelin in rats at 10 mg/kg per day, p.o.; decreases cortical and hippocampal amyloid-β burden in the APPsw (Tg2576) and PS1/APPsw transgenic mouse models of Alzheimer’s disease at 0.03% (w/w) in the diet for 17 and 10 months, respectively; reduces infarct volume in a rat model of MCAO-induced focal cerebral ischemia at 3.2 mg/kg, s.c.
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