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Cayman Chemical NIlvadIpIn 100mg
SDP

Supplier:  Cayman Chemical 21243100 MG

Encompass_Preferred

A JAK1 and JAK2 inhibitor (IC50s 0 0059 and 0 0057 UM respectively) selective for JAK1 and JAK2 over JAK3 TYK2 c-Met and Chk2 (IC50s 0 4 0 053 10 and 1 UM respectively) inhibits IL-6-induced phosphorylation of STAT3 in isolated human PBMCs and rat whole blood (IC50s 0 044 and 0 128 UM respectively) reduces disease severity in a type II collagen-induced mouse model of arthritis at 3 and 10 mg/kg decreases lung macrophage infiltration and disease severity in rhesus monkeys infected with SARS-CoV-2 at 4 mg/animal

Catalog No. 50-298-1053


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