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Apexbio Technology LLC Nimorazole 200mg
Supplier: Apexbio Technology LLC B3510200
Nimorazole (6506-37-2) is a nitroimidazole-based small-molecule radiosensitizer designed to enhance cellular radiosensitivity in hypoxic tumor environments Nimorazole exerts its biological activity primarily through metabolic reduction under hypoxic conditions forming reactive intermediates that interact with cellular DNA and augment the effects of radiation therapy In experimental studies nimorazole demonstrates radiosensitizing properties with IC50 values commonly reported in the low millimolar range in vitro although the exact value varies by cell line and context Based on these pharmacological properties nimorazole holds research potential in oncology applications particularly for investigating radiotherapeutic strategies targeting hypoxia-affected neoplastic tissues such as head and neck squamous cell carcinoma
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