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Medchemexpress LLC Nimustine (hydrochloride) | 55661-38-6 | 98.2% | 309.15 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY13703A

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Nimustine hydrochloride (ACNU) is the hydrochloride salt form of Nimustine. It functions as an alkylating agent, inducing DNA double-strand breaks and inter-strand crosslinks. This action activates the DNA damage response signaling pathway and the p38 MAPK/JNK signaling pathway, demonstrating antitumor activity.

  • Acts as an alkylating agent
  • Induces DNA double-strand breaks and inter-strand crosslinks
  • Activates DNA damage response signaling pathway
  • Activates p38 MAPK/JNK signaling pathway
  • Exhibits antitumor activity
  • Induces apoptosis in LN-229 cells
  • Inhibits tumor growth in C3H/HeN mouse models

Catalog No. 50-003-51958


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