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Medchemexpress LLC Nimustine hydrochloride (ACNU) | 55661-38-6 | 98.2% | 309.15 | 1 ML
SDP

Catalog No. 5000350287
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Nimustine hydrochloride (ACNU) is the hydrochloride salt form of Nimustine. It functions as an alkylating agent by inducing DNA double-strand breaks (DSBs) and inter-strand crosslinks (ICLs), which activates the DNA damage response (DDR) signaling pathway. It also activates the p38 MAPK/JNK signaling pathway and demonstrates antitumor activity.

  • Induces DNA double-strand breaks and inter-strand crosslinks.
  • Activates DNA damage response signaling.
  • Activates p38 MAPK/JNK signaling.
  • Demonstrates antitumor activity.
  • Exhibits cytotoxicity against human U87MG cells.
  • Induces apoptosis in LN-229 cells.

Catalog No. 50-003-50287 Supplier Medchemexpress LLC Supplier No. HY13703A10MM/1ML
May include imposed supplier surcharges.
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Nimustine hydrochloride (ACNU) is the hydrochloride salt form of Nimustine. It functions as an alkylating agent by inducing DNA double-strand breaks (DSBs) and inter-strand crosslinks (ICLs), which activates the DNA damage response (DDR) signaling pathway. It also activates the p38 MAPK/JNK signaling pathway and demonstrates antitumor activity.

  • Induces DNA double-strand breaks and inter-strand crosslinks.
  • Activates DNA damage response signaling.
  • Activates p38 MAPK/JNK signaling.
  • Demonstrates antitumor activity.
  • Exhibits cytotoxicity against human U87MG cells.
  • Induces apoptosis in LN-229 cells.

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