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Selleck Chemical LLC Niraparib (MK-4827) S2741-50mg
SDP

Catalog No. 503112738
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Niraparib (MK-4827) is a selective inhibitor of PARP1/2 with IC50 of 3 8 nM/2 1 nM with great activity in cancer cells with mutant BRCA-1 and BRCA-2 It is 330-fold selective against PARP3 V-PARP and Tank1 Niraparib can form PARP DNA complexes resulting in DNA damage apoptosis and cell death Phase 3

Catalog No. 50-311-2738 Supplier Selleck Chemical LLC Supplier No. S274150MG
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Niraparib (MK-4827) is a selective inhibitor of PARP1/2 with IC50 of 3 8 nM/2 1 nM with great activity in cancer cells with mutant BRCA-1 and BRCA-2 It is 330-fold selective against PARP3 V-PARP and Tank1 Niraparib can form PARP DNA complexes resulting in DNA damage apoptosis and cell death Phase 3

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