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  6. Nisin, 900 I.U./mg

Nisin, 900 I.U./mg

Catalog No. AAJ6637003
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Quantity:
1 g
5 g
25 g

Description

Nisin, CAS # 1414-45-5, is a polycyclic peptide derived from and produced by Lactococcus lactis that shows antibacterial activity against gram-positive bacteria. | CAS: 1414-45-5 | C143H230N42O37S7 | 3354.09 g/mol

Nisin, 900 I.U./mg is commonly used as a food preservative. It is also used as a selective agent in cell culture for the isolation of gram-negative bacteria, yeast, and molds. Nisin has been used in bioassays to study posttranslational modification. It binds and interferes with the permeability of the cytoplasmic membrane.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Nisin is a broad-spectrum polycyclic peptide derived from and produced by Lactococcus lactis that shows antibacterial activity against gram-positive bacteria Nisin binds lipid II in the cell membrane. After binding it can insert into the membrane, creating a pore Nisin can efficiently inhibit the growth of gram-positive bacteria, and resistance is rarely observed

Application

  • Nisin is commonly used as a selective compound in cell culture to isolate gram-negative bacteria, yeast, and molds (a type of fungus)
  • It has been used in bioassays to study posttranslational modification
  • This compound has the ability to bind and interfere with the permeability of the cytoplasmic membrane
  • It is used to study the assembly and stability of nisin-lipid II pore complexes
  • This compound is used in in vitro experiments to form targeted pores in cell membranes that are mediated by lipid II
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 1414-45-5
Molecular Formula C143H230N42O37S7
Molecular Weight (g/mol) 3354.09
MDL Number MFCD00131724
InChI Key NVNLLIYOARQCIX-OAXMGIFASA-N
PubChem CID 131847819
SMILES CCC(C)C1C(=O)NC(=C)C(=O)NC(C(=O)NC(CSCC(C(=O)N1)NC(=O)C(=CC)NC(=O)C(C(C)CC)N)C(=O)NC2C(SCC(NC(=O)CNC(=O)C3CCCN3C2=O)C(=O)NC(CCCCN)C(=O)NC4C(SCC(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC4=O)C)CC(C)C)CCSC)C(=O)NC(CC(=O)N)C(=O)NC(CCSC)C(=O)NC(CCCCN)C(=O)NC5C(

Specifications

Type Nisin
Physical Form Powder
Color Brown
Quantity 1 g
Flash Point >110°C (230°F)
Boiling Point 2967°C
Merck Index 14,6564
Solubility Information Soluble in water
Formula Weight 3354.06
Chemical Name or Material Nisin, 900 I.U./mg

Safety and Handling

EINECSNumber 215-807-5
RTECSNumber QU3340000
TSCA No
storageNote1 2° to 8°C
Recommended Storage Keep cold
SDS

RUO – Research Use Only

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