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Apexbio Technology LLC Nisoldipine 63675-72-9 10mM (in 1mL DMSO)

Supplier: Apexbio Technology LLC B19895.1

Nisoldipine (CAS 63675-72-9) is a dihydropyridine-based calcium channel blocker selective for the voltage-dependent L-type calcium channel Cav1 2 It inhibits Cav1 2-mediated calcium influx with an IC50 of approximately 10 nM By modulating calcium entry nisoldipine is frequently utilized in cardiovascular research to study vascular smooth muscle contraction calcium signaling pathways and cardiovascular pharmacology Its selective blockade helps elucidate the functional importance of Cav1 2 channels under physiological and pathological conditions
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