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Medchemexpress LLC NITD-688 | 2407227-31-8 | 98.0% | 500.68 | 25 MG
Supplier: Medchemexpress LLC 25MGHY138543
NITD-688 is an orally active pan-serotype inhibitor of the dengue virus NS4B protein. It is utilized in dengue virus (DENV) research and demonstrates antiviral activity against all four serotypes of DENV.
- Orally active pan-serotype inhibitor of the dengue virus NS4B protein
- Utilized in dengue virus (DENV) research
- Exhibits antiviral activity against all four serotypes of DENV
- Shows antiviral activity against DENV-2 infected PBMCs with an EC50 value of 0.94 nM
- Directly binds to wild-type but not mutant NS4B protein
- Demonstrates antiviral efficacy in infected AG129 mice
- Well tolerated in rats and dogs
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