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Medchemexpress LLC NITD-688 | 2407227-31-8 | 98.04% | 500.68 | 1 MG
Supplier: Medchemexpress LLC HY1385431MG
NITD-688 is an orally active pan-serotype inhibitor of the dengue virus NS4B protein, used in the research of dengue virus (DENV).
- Antiviral activity against all four DENV serotypes (EC50 values of 8 to 38 nM)
- Antiviral activity against DENV-2 infected PBMCs (EC50 value of 0.94 nM)
- Directly binds to wild-type NS4B protein
- Excellent antiviral efficacy in infected AG129 mice
- Well tolerated in rats and dogs
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