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Medchemexpress LLC NITD008 (7-Deaza-2'-C-acetylene-adenosine) | 1044589-82-3 | 98.0% | 1 ML
SDP

Catalog No. 5000339444
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NITD008 is a potent and selective flaviviruse inhibitor, effectively targeting Dengue Virus Type 2 (DENV-2) with an EC50 of 0.64 μM. It also functions as a versatile click chemistry reagent, containing an Alkyne group suitable for copper-catalyzed azide-alkyne cycloaddition (CuAAc). Beyond DENV-2, NITD008 broadly inhibits various flaviviruses like West Nile, yellow fever, and Poissan virus. Demonstrating oral bioavailability and favorable pharmacokinetics, it has shown efficacy in suppressing viremia and cytokine elevation in vivo.

  • Potent and selective flavivirus inhibitor
  • Inhibits Dengue Virus Type 2 (DENV-2) (EC50 0.64 μM)
  • Functions as a click chemistry reagent with an Alkyne group
  • Orally bioavailable with favorable pharmacokinetics
  • Effective in vivo against flaviviruses

Catalog No. 50-003-39444 Supplier Medchemexpress LLC Supplier No. HY1295710MM/1ML
May include imposed supplier surcharges.
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NITD008 is a potent and selective flaviviruse inhibitor, effectively targeting Dengue Virus Type 2 (DENV-2) with an EC50 of 0.64 μM. It also functions as a versatile click chemistry reagent, containing an Alkyne group suitable for copper-catalyzed azide-alkyne cycloaddition (CuAAc). Beyond DENV-2, NITD008 broadly inhibits various flaviviruses like West Nile, yellow fever, and Poissan virus. Demonstrating oral bioavailability and favorable pharmacokinetics, it has shown efficacy in suppressing viremia and cytokine elevation in vivo.

  • Potent and selective flavivirus inhibitor
  • Inhibits Dengue Virus Type 2 (DENV-2) (EC50 0.64 μM)
  • Functions as a click chemistry reagent with an Alkyne group
  • Orally bioavailable with favorable pharmacokinetics
  • Effective in vivo against flaviviruses

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