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Cayman Chemical NItrate Reductase Enzyme Prep
SDP

Supplier:  Cayman Chemical 7800101 EA

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A VEGFR1 VEGFR2 and EGFR inhibitor (IC50s 0.7 0.03 and 0.4 UM respectively) selective for these kinases over PDGFRB FGFR1 and HER2 (IC50s 3.4 >100 and >100 UM respectively) and MEK Cdk2 IGF-1R Akt and Tie2 (IC50s >10 >10 >20 >20 and >100 UM respectively) selectively inhibits VEGF- or EGF-induced proliferation of HUVECs over FGF-induced proliferation of HUVECs (IC50s 0.05 0.05 and 1.5 UM respectively) reduces tumor volume in a Calu-6 NSCLC mouse xenograft model at 100 mg/kg inhibits training-induced increases in collateral blood flow and white gastrocnemius muscle capillarity in exercise-trained rats

Catalog No. 50-289-3265


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