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Cayman Chemical NItrIte Stndard 1ea
Supplier: Cayman Chemical 7800161 EA
A GCGR GLP-1R and GIP receptor agonist induces cAMP accumulation in HEK293 cells expressing the human GCGR GLP-1R or GIP receptor (EC50s 5.79 0.775 and 0.0643 nM respectively) decreases plasma glucose levels in an intraperitoneal glucose tolerance test in mice from 0.1-30 nmol/kg decreases body weight calorie intake fat mass and lean mass in a mouse model of diet-induced obesity acute administration delays gastric emptying and chronic administration for 10 days decreases food intake and body weight in mice
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