ABclonal Technology NKX2-1 Rabbit mAb

Supplier:  ABclonal Technology A2224720UL

This gene encodes a protein initially identified as a thyroid-specific transcription factor The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis Mutations and deletions in this gene are associated with benign hereditary chorea choreoathetosis congenital hypothyroidism and neonatal respiratory distress and may be associated with thyroid cancer Multiple transcript variants encoding different isoforms have been found for this gene This gene shares the symbol alias TTF1 with another gene transcription termination factor 1 which plays a role in ribosomal gene transcription

Catalog No. 50-000-05945