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Selleck Chemical LLC NLRP3/AIM2-IN-3 E5801-25MG
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Catalog No. 5000042713
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NLRP3/AIM2-IN-3 (compound 59) is a potent inhibitor with species-specific effects on NLRP3 and AIM2 inflammasome-mediated pyroptosis It demonstrates potent inhibition of pyroptosis in THP-1 macrophages stimulated with LPS/nigericin with an IC50 of 0 077 M It also disrupts the interaction between NLRP3 or AIM2 and the adaptor protein ASC effectively preventing ASC oligomerization and blocking inflammasome assembly

Catalog No. 50-000-42713 Supplier Selleck Chemical LLC Supplier No. E580125MG
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NLRP3/AIM2-IN-3 (compound 59) is a potent inhibitor with species-specific effects on NLRP3 and AIM2 inflammasome-mediated pyroptosis It demonstrates potent inhibition of pyroptosis in THP-1 macrophages stimulated with LPS/nigericin with an IC50 of 0 077 M It also disrupts the interaction between NLRP3 or AIM2 and the adaptor protein ASC effectively preventing ASC oligomerization and blocking inflammasome assembly

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