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AdipoGen NMNAT1 hHishighly active
Supplier: AdipoGen AG40T0092C050
Protein. Human full-length NMNAT1 aa 1-279 is fused at the N-terminus to a His-tag. Source E. coli. Endotoxin content N/A. Liquid. In 50mM sodium phosphate, pH8.0, containing 300mM sodium chloride, 2mM DTT and 10% glycerol. Purity >95% SDS-PAGE. Nuclear NMNAT isoform. Catalyzes the formation of NAD from nicotinamide mononucleotide NMN and ATP. It can also use the deamidated form of nicotinic acid mononucleotide NAMN as substrate with the same efficiency. Interacts with PARP-1/ARTD1. Protects against axonal degeneration following mechanical or toxic insults. Widely expressed.
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