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Abcam NNC 711, GAT-1 inhibitor, 10MG
Supplier: Abcam AB12036410MG
MW 386.9 Da, Purity >99%. Potent and selective GAT-1 GABA uptake inhibitor. (IC₅₀ values are 0.04 (hGAT-1), 171 (rGAT-2), 1700 (hGAT-3) and 622 μM (hBGT-1)). Selective over a range of other neurotransmitter receptor binding sites, uptake sites and ion channels in vitro. Potent anticonvulsant, neuroprotectant and cognitive enhancer in vivo. Also available in simple stock solutions (ab146719) - add 1 ml of water to get an exact, ready-to-use concentration.
The product is subject to the following: Abcam Restricted Use Statement
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