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Cayman Chemical nngenIn H 500ug
SDP

Supplier:  Cayman Chemical 33145500 UG

Encompass_Preferred

An ABHD12 inhibitor (IC50 11 nM) inhibits ABHD-dependent hydrolysis of lyso-PS in mouse brain membrane lysates (IC50 2.8 nM) and human THP-1 cells increases levels of CCL3 CCL4 TNF-a and IL-1B in M1-polarized THP-1 macrophages increases levels of 1-stearoyl-2-hydroxy-sn-glycero-3-PS 1-arachidonoyl-2-hydroxy-sn-glycero-3-PS 1-docosanoyl-2-hydroxy-sn-glycero-3-PS 1-stearoyl-2-arachidonoyl-sn-glycero-3-PS and 1-oleoyl-2-arachidonoyl-sn-glycero-3-PS in mouse brain at 30 mg/kg per day for four weeks increases levels of CCL2 CCL3 and CCL5 in BALF and decreases survival in a mouse model of infection with LCMV clone 13 at 30 mg/kg

Catalog No. 50-294-9487


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