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Cayman Chemical NonIdet P-40 asy Reagent1 6mL

Supplier: Cayman Chemical 6000096 ML

A GCGR antagonist (IC50s 3.7 and 179 nM in the absence and presence of MgCl2 respectively) prevents glucagon-induced increases in IL-1B and IL-6 levels in and levels secreted from HepG2 cells at 3.7 nM inhibits glucagon-induced increases in the mRNA encoding C3 CRP and fibrinogen in HepG2 cells inhibits glucagon-induced increases in the hepatic levels of NLRP3 phosphorylated NF-KB and phosphorylated Stat3 in mice at 1 UM in drinking water
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