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Medchemexpress LLC Norfluoxetine hydrochloride | 57226-68-3 | 99.6% | 331.76 | 25 MG
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Supplier:  Medchemexpress LLC 25MGHYW011235

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Norfluoxetine hydrochloride is an active N-demethylated metabolite of Fluoxetine. Fluoxetine, a selective serotonin (5-HT) reuptake inhibitor, is metabolized to Norfluoxetine hydrochloride by cytochrome P450 (CYP) 2D6, CYP2C19, and CYP3A4. This compound inhibits 5-HT uptake and CaV3.3 T current with an IC50 of 5 μM. Additionally, Norfluoxetine hydrochloride demonstrates anticonvulsant activity.

  • Active N-demethylated metabolite of fluoxetine.
  • Inhibits 5-HT uptake.
  • Inhibits CaV3.3 T current (IC50 = 5 μM).
  • Exhibits anticonvulsant activity.

Catalog No. 50-003-66717


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