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Medchemexpress LLC Norleual TFA | 6404-28-0 | >99.9% | 888.97 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYP1415A5MG

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Norleual TFA is an angiotensin (Ang) IV analog and a hepatocyte growth factor (HGF)/c-Met inhibitor with an IC50 of 3 pM. It also functions as an AT4 receptor antagonist and demonstrates potent antiangiogenic activities.

  • Reduces HGF-dependent c-Met and Gab1 phosphorylation
  • Attenuates HGF-initiated association between Gab1 and c-Met
  • Inhibits HGF-dependent c-Met activation and downstream signaling
  • Inhibits HGF-dependent signaling, proliferation, migration, and invasion
  • Suppresses pulmonary colonization by B16-F10 murine melanoma cells

Catalog No. 50-004-22964


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