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Medchemexpress LLC (±)-Nornicotine-d4 | 66148-18-3 | 152.23 | 5 MG
Supplier: Medchemexpress LLC HYW002112S5MG
(±)-Nornicotine-d4 is the deuterium labeled form of (±)-Nornicotine, a major metabolite of Nicotine. It functions as a partial nAChRs agonist, specifically activating receptor subtypes containing α7 and α6 subunits. This compound is known to disrupt β-catenin and ZO-1, and induces F-actin depolymerization. It also supports self-administration behavior, making it valuable for research in atherosclerosis, Alzheimer's disease, and schizophrenia. Deuteration, the process of incorporating stable heavy isotopes, has been shown to potentially affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled compound
- Major metabolite of nicotine
- Partial nAChRs agonist (α7 and α6 subunits)
- Disrupts β-catenin and ZO-1
- Induces F-actin depolymerization
- Supports self-administration behavior
- Useful in research for atherosclerosis, Alzheimer's disease, and schizophrenia
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