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Medchemexpress LLC (±)-Nornicotine-d4 | 66148-18-3 | 152.23 | 50 MG
Supplier: Medchemexpress LLC HYW002112S50MG
(±)-Nornicotine-d4 is the deuterium labeled form of (±)-Nornicotine, a major metabolite of Nicotine. It acts as a partial nAChRs agonist, specifically targeting receptor subtypes containing α7 and α6 subunits. This compound has been shown to disrupt β-catenin and ZO-1, and induce F-actin depolymerization. Deuterium labeling can affect the pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled form of nornicotine
- Major metabolite of nicotine
- Acts as a partial nAChRs agonist
- Activates receptor subtypes containing α7 and α6 subunits
- Disrupts β-catenin and ZO-1
- Induces F-actin depolymerization
- Supports self-administration behavior
- Applicable in research for atherosclerosis, Alzheimer's disease, and schizophrenia
- Potential to affect pharmacokinetic and metabolic profiles
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