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Medchemexpress LLC Nortriptyline hydrochloride | 894-71-3 | 100.0% | 500 MG
SDP

Supplier:  Medchemexpress LLC HYB1417500MG

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Nortriptyline hydrochloride, a tricyclic antidepressant and the main active metabolite of Amitriptyline, acts as a potent autophagy inhibitor and demonstrates anticancer effects.

  • Tricyclic antidepressant
  • Potent autophagy inhibitor
  • Has anticancer effects
  • Blocks the reuptake of Norepinephrine more potently than Serotonin
  • Markedly reduces the viability of TCCSUP and mouse MBT-2 bladder cancer cells in a concentration- and time-dependent manner
  • Induces cell cycle arrest and apoptosis in TCCSUP and MBT-2 cells
  • Induces both intrinsic and extrinsic apoptosis in bladder cancer cells
  • Inhibits the growth of bladder tumors in mice inoculated with MBT-2 cells

Catalog No. 50-004-13429


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