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Cayman Chemical -Notkaton 100mg
Supplier: Cayman Chemical 24910100 MG
A B1- and B2-AR antagonist (Kis 2.6 and 4.8 nM respectively) partial agonist of the B3-AR antagonist of the 5-HT1A receptor (Ki 81.1 nM for inhibition of 5-HT-stimulated GTPYS binding) inhibits isoproterenol-induced tachycardia in anesthetized cats (ED50 1.8 Ug/kg) decreases mean blood pressure in conscious spontaneously hypertensive rats at 30 mg/kg per day
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