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Cayman Chemical NotogInsenosIde R1 50mg
Supplier: Cayman Chemical 2969150 MG
A saponin; decreases serum total cholesterol, triacylglycerol, and oxLDL levels, as well as reduces atherosclerotic lesion area and lipid deposition in the aortic root of ApoE-/- mice fed a Western diet at 25 mg/kg per day for 8 weeks; inhibits apoptosis of hippocampal neurons and reduces infarct size in a rat model of cerebral ischemia-reperfusion injury induced by bilateral common carotid artery occlusion at 100 mg/kg; decreases colonic NF-ĸB and MPO activities and TNF-α and IL-6 levels, as well as reduces colonic shortening, tissue damage, and inflammatory cell infiltration in a DSS-induced mouse model of colitis at 25 mg/kg per day for 7 days
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