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Medchemexpress LLC NP118809 | 41332-24-5 | 98.73% | C₃₂H₃₂N₂O | 200 MG
SDP

Supplier:  Medchemexpress LLC HY14462200MG

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NP118809 is a potent N-type calcium channel blocker with an IC₅₀ of 0.11 μM, and also inhibits L-type calcium channels less potently with an IC₅₀ of 12.2 μM. It is intended for research use only.

  • Potent N-type calcium channel blocker (IC₅₀ of 0.11 μM).
  • Inhibits L-type calcium channels (IC₅₀ of 12.2 μM).
  • Shows significant analgesic activity in the phase IIA portions of the rat formalin model (25 mg/kg, i.p.).
  • Results in 80.3% inhibition of mechanical allodynia and 96.3% inhibition of thermal hyperalgesia in the rat spinal nerve ligation model (30 mg/kg, p.o.).
  • Available in solid form, light yellow to yellow in color.

Catalog No. 50-003-54628


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