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Medchemexpress LLC Nrf2 degrader 1 | 3025286-00-1 | 98.8% | 826.92 | 50 MG
SDP

Catalog No. 5000392922
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Nrf2 degrader 1 (compound 1) is a PROTAC Nrf2 degrader with a DC50 of 0.1-1 μM in huH1 cells. It inhibits cancer cell growth for A549 and LK-2 cells with IC50 values of 100 nM and 40 nM, respectively. It can be used for the study of liver cancer, non-small cell lung cancer (NSCLC), and squamous cell carcinoma of lung cancer. The compound structure consists of an Nrf2 Target protein ligand, a Cereblon ligand, and a linker. It is intended for research use only.

  • Inhibits cancer cell viability with IC50 values of 100 nM for A549 (lung, carcinoma) and 40 nM for LK-2 (squamous cell carcinoma) after 3 days.

Catalog No. 50-003-92922 Supplier Medchemexpress LLC Supplier No. HY16230750MG
May include imposed supplier surcharges.
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Nrf2 degrader 1 (compound 1) is a PROTAC Nrf2 degrader with a DC50 of 0.1-1 μM in huH1 cells. It inhibits cancer cell growth for A549 and LK-2 cells with IC50 values of 100 nM and 40 nM, respectively. It can be used for the study of liver cancer, non-small cell lung cancer (NSCLC), and squamous cell carcinoma of lung cancer. The compound structure consists of an Nrf2 Target protein ligand, a Cereblon ligand, and a linker. It is intended for research use only.

  • Inhibits cancer cell viability with IC50 values of 100 nM for A549 (lung, carcinoma) and 40 nM for LK-2 (squamous cell carcinoma) after 3 days.

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