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Medchemexpress LLC Ns-638 | 150493-34-8 | 99.8% | 325.72 | C15H11ClF3N3 | 25 MG
SDP

Supplier:  Medchemexpress LLC HY10142825MG

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NS-638 is a small nonpeptide calcium-channel blocker used in research to inhibit K+-stimulated intracellular calcium elevation. It demonstrates in vitro potency (IC50 3.4 μM) and has shown neuroprotective efficacy in a mouse middle cerebral artery occlusion model.

  • Blocks K+-stimulated intracellular Ca2+ elevation (IC50 3.4 μM).
  • Reversibly inhibits N- and L-type Ca2+ channels in cultured neurons.
  • Demonstrates activity in vitro and reduces infarct volume in animal models.
  • High purity solid, white to off-white, suitable for analytical and biological assays.
  • Available as solid quantities and as a DMSO solution for convenient dosing.
  • Store powder and solutions at recommended low temperatures to preserve stability.

Catalog No. 50-002-48512


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