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Medchemexpress LLC Ns-638 | 150493-34-8 | 99.8% | 325.72 | C15H11ClF3N3 | 25 MG

Supplier: Medchemexpress LLC HY10142825MG
NS-638 is a small nonpeptide calcium-channel blocker used in research to inhibit K+-stimulated intracellular calcium elevation. It demonstrates in vitro potency (IC50 3.4 μM) and has shown neuroprotective efficacy in a mouse middle cerebral artery occlusion model.
- Blocks K+-stimulated intracellular Ca2+ elevation (IC50 3.4 μM).
- Reversibly inhibits N- and L-type Ca2+ channels in cultured neurons.
- Demonstrates activity in vitro and reduces infarct volume in animal models.
- High purity solid, white to off-white, suitable for analytical and biological assays.
- Available as solid quantities and as a DMSO solution for convenient dosing.
- Store powder and solutions at recommended low temperatures to preserve stability.
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