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Medchemexpress LLC NSC-87877 (disodium) | 56932-43-5 | 98.0% | 503.42 | 50 MG
Supplier: Medchemexpress LLC HY18756A50MG
NSC-87877 disodium is a potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases, with IC50 values of 0.318 μM and 0.355 μM for Shp2 and Shp1, respectively. It also inhibits dual-specificity phosphatase 26 (DUSP26).
- Potent inhibitor of Shp2 and Shp1 protein tyrosine phosphatases
- Inhibits dual-specificity phosphatase 26 (DUSP26)
- Inhibits DUSP26 function in NB cell lines
- Results in increased p53 phosphorylation and activation
- Possesses excellent anti-neuroblastoma activity in vivo
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