ProSci NTAQ1 Recombinant Protein

Catalog No.	Quantity
16-593-795	0.05 mg

Catalog No. 16-593-795 Supplier ProSci Supplier No. 925060050

Description

Recombinant Protein

This recombinant protein can be used for biological assays. For research use only.

Human protein N-terminal glutamine amidohydrolase (WDYHV1) is an enzyme that in humans is encoded by the WDYHV1 gene, belongs to the NTAQ1 family.WDYHV1 mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, which is an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. However,it does not act on substrates with internal or C-terminal glutamine andnon-glutamine residues in any position. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.

Specifications

• Accession Number: Q96HA8
• Gene ID (Entrez): 55093
• Molecular Weight (g/mol): 49.8 kDa
• Quantity: 0.05 mg
• Source: E. coli
• Common Name: WDYHV motif containing 1
• Gene Symbol: WDYHV1
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: N-GST tag
• Sequence: Met1-Cys205
• Content And Storage: Store at -20°C, stable for 6 months after receipt. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Purity or Quality Grade: >95% as determined by reducing SDS-PAGE. Endotoxin level less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
• Synonym: Protein N-terminal glutamine amidohydrolase, WDYHV1, Protein NH2-terminal glutamine deamidase, N-terminal Gln amidase, Nt(Q)-amidase, C8orf32, NTAQ1, REF: C1009