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Cayman Chemical Antazoline (hydrochloride), Purity: ≥98%, CAS: 2508-72-7, 5 g
SDP

Catalog No. 502964086
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A histamine H1 receptor antagonist (Ki = 38.4 nM in cell membranes expressing human recombinant H1 receptors); reduces histamine-induced IL-6 and IL-8 production in human conjunctival epithelial cells (IC50s = 1 and 0.652 μM, respectively); prevents anaphylaxis in rabbits sensitized to egg albumin and increases survival in a guinea pig model of histamine-induced bronchospasm; eliminates atrial fibrillation induced by acetylcholine and isoproterenol in isolated rabbit hearts by increasing the atrial effective refractory period and interatrial conduction time in a dose-dependent manner; binds to NMDA receptors (Ki = 13 μM) and reduces glutamate-induced toxicity in cerebellar granule cells (EC50 = 13 μM)

Catalog No. 50-296-4086 Supplier Cayman Chemical Supplier No. 234155 G
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A histamine H1 receptor antagonist (Ki = 38.4 nM in cell membranes expressing human recombinant H1 receptors); reduces histamine-induced IL-6 and IL-8 production in human conjunctival epithelial cells (IC50s = 1 and 0.652 μM, respectively); prevents anaphylaxis in rabbits sensitized to egg albumin and increases survival in a guinea pig model of histamine-induced bronchospasm; eliminates atrial fibrillation induced by acetylcholine and isoproterenol in isolated rabbit hearts by increasing the atrial effective refractory period and interatrial conduction time in a dose-dependent manner; binds to NMDA receptors (Ki = 13 μM) and reduces glutamate-induced toxicity in cerebellar granule cells (EC50 = 13 μM)

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