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Cayman Chemical ntIlImIcInsulfate 50mg

Supplier: Cayman Chemical 2666650 MG

An orally bioavailable inhibitor of STAT3 (32 and 62 inhibition at 10 and 20 UM respectively in MDA-MB-231 cells in a luciferase reporter assay) inhibits proliferation of MCF-7 and MDA-MB-231 breast cancer and AsPC-1 and PANC-1 pancreatic cancer cells (IC50s 0.91 1.64 1.9 and 1.08 UM respectively) inhibits tumor growth in a breast cancer mouse xenograft model at doses of 7.5 mg/kg i.p. or 25 mg/kg p.o. inhibits tumor growth in an orthotopic mouse model of squamous cell carcinoma
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