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Cayman Chemical ntImycIn A Complex 50mg
SDP

Supplier:  Cayman Chemical 3479950 MG

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An ERK inhibitor (IC50 2 7 nM for ERK2) selective for ERK over a panel of 465 kinases reduces RSK phosphorylation in mutant B-RAF-expressing A375 melanoma and mutant K-Ras-expressing HCT116 colorectal cancer cells (IC50s 3 3 and 4 nM respectively) inhibits proliferation in a panel of cancer cell lines including melanoma colorectal and lung cancer cells reduces tumor growth in A375 Calu-6 and COLO 205 mouse xenograft models

Catalog No. 50-291-1176


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