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Enzo Life Sciences NU1025 (25mg). CAS: 90417-38-2
SDP

Supplier:  Enzo Life Sciences ALX270370M025

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PARP-1 inhibitor. A potent poly(ADP-ribose) polymerase 1 (PARP-1) inhibitor (IC50=400nM) that potentiates the cytotoxicity of various DNA-active agents, including the DNA-methylating compound MTIC, the DNA strand break-inducing drug temozolomide (ALX-420-044), topotecan (ALX-350-133), bleomycin (BML-AP302), and ionizing radiation effective in murine L1210 leukemia cells, CHO, and in a variety of human tumor cell lines. Alternative name: 8-Hydroxy-2-methylquinazoline-4-one. Formula: C9H8N2O2. MW: 176.2. Purity: ≥98% (HPLC). Appearance: Off-white to purple solid. Solubility: Soluble in DMSO (25mg/ml). This solution can be further diluted 1:100 in tissue culture medium before use. Long Term Storage: -20°C.

Catalog No. 50-200-8516


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