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Apexbio Technology LLC Nucleozin 341001-38-5 200mg
Supplier: Apexbio Technology LLC A3670200
Nucleozin (CAS 341001-38-5) is a small-molecule inhibitor targeting influenza A virus nucleoprotein (NP) It is designed to block NP nuclear accumulation thereby inhibiting a critical step in the viral replication cycle Nucleozin exerts its biological activity primarily through inducing NP aggregation and preventing its nuclear localization In in vitro studies using MDCK cells infected with influenza A variants Nucleozin demonstrates antiviral inhibition with EC50 values of 0 069 M for A/WSN/33 (H1N1) 0 16 M for H3N2 and 0 33 M for Vietnam/1194/04 (H5N1) Based on these pharmacological properties Nucleozin holds research potential in influenza antiviral development
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