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Abcam (-)-Nutlin-3, p53-MDM2 binding inhibitor, 25MG
Supplier: Abcam AB14442825MG
MW 581.5 Da, Purity >98%. Potent p53-MDM2 binding inhibitor (IC50 = 90 nM). Enantiomer of (+)-Nutlin-3 (ab144426). Shows antiproliferative effects (IC50 values are 2.2 and 1.3 µM for human skin and murine fibroblasts respectively). Shows antitumor effects *in vivo.* Orally active.
The product is subject to the following: Abcam Restricted Use Statement
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