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Abcam (+)-Nutlin-3, p53-MDM2 binding inhibitor, 5MG

Supplier:  Abcam AB1444265MG

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MW 581.5 Da, Purity >98%. p53-MDM2 binding inhibitor (IC₅₀ = 13 μM). Less potent enantiomer of (-)-Nutlin-3 (Asc-4428 ). Shows antiproliferative effects (IC₅₀ values are 2.2 and 1.3 μM for human skin and murine fibroblasts respectively). Shows antitumor effects in vivo. Orally active.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-270-5743


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