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Medchemexpress LLC Nutlin (3a) | 675576-98-4 | 99.1% | 581.49 | 50 MG
Supplier: Medchemexpress LLC 50MGHY10029
Nutlin-3a (Rebemadlin) is a potent and selective MDM2 inhibitor, acting as the active enantiomer of Nutlin-3. It functions by inhibiting MDM2-p53 interactions, thereby stabilizing the p53 protein and inducing both cell autophagy and apoptosis. This compound holds potential for research into TP53 wild-type ovarian carcinomas.
- Potent murine double minute (MDM2) inhibitor with an IC50 of 90 nM.
- Inhibits MDM2-p53 interactions.
- Stabilizes the p53 protein.
- Induces cell autophagy and apoptosis.
- Potential for the study of TP53 wild-type ovarian carcinomas.
- Highly selective MDM2 antagonist and p53 inducer.
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