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Medchemexpress LLC Nutlin-3a (Rebemadlin) | 675576-98-4 | 581.49 g/mol | C30H30Cl2N4O4 | 500 MG
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Supplier:  Medchemexpress LLC HY10029500MG

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Nutlin-3a (Rebemadlin) is a research-grade small molecule that antagonizes MDM2, disrupting the MDM2-p53 interaction to stabilize wild-type p53 and trigger apoptosis and autophagy. It is used in preclinical studies to probe p53-dependent cancer biology and cellular stress responses.

  • Inhibits MDM2-p53 interaction.
  • Stabilizes wild-type p53 protein.
  • Induces apoptosis and autophagy in p53-competent cells.
  • Reported IC50 approximately 90 nM in biochemical assays.
  • Molecular formula C30H30Cl2N4O4; molecular weight 581.49 g/mol.
  • Suitable for in vitro and preclinical research applications.

Catalog No. 50-002-14389


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