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Apexbio Technology LLC NVR 3-778 1445790-55-5 1mg
Supplier: Apexbio Technology LLC A99551
NVR 3-778 (CAS 1445790-55-5) is a small-molecule modulator targeting the hepatitis B virus (HBV) core protein It is designed to interfere with HBV capsid assembly thereby inhibiting viral genome encapsidation and replication NVR 3-778 exerts its biological activity primarily by disrupting capsid formation and reducing viral replication In in vitro studies NVR 3-778 demonstrates antiviral inhibition with a half-maximal inhibitory concentration (IC50) reported in the low micromolar range Based on these pharmacological properties NVR 3-778 holds research potential in the investigation of HBV biology and the development of alternative therapeutic approaches for chronic hepatitis B infection
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