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Medchemexpress LLC Nvs-sm2 | 1562333-92-9 | 99.2% | 406.52 | C23H30N6O | 5 MG
SDP

Catalog No. 5000263333
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NVS-SM2 is a potent small-molecule SMN2 splicing enhancer used in spinal muscular atrophy (SMA) research. It is orally active and brain-penetrant, promotes U1-pre-mRNA association to increase exon 7 inclusion, and restores functional survival motor neuron (SMN) protein levels (reported EC50 ≈ 2 nM). Supplied as a high-purity solid and available in solution formats for experimental use.

  • Potent SMN2 splicing enhancer with low-nanomolar activity.
  • Orally active and brain-penetrant chemical probe.
  • Promotes exon 7 inclusion and increases SMN protein expression.
  • Supplied as a solid with high reported purity.
  • Available in multiple sizes and DMSO solution formats for flexibility.

Catalog No. 50-002-63333 Supplier Medchemexpress LLC Supplier No. HY1115205MG
May include imposed supplier surcharges.
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NVS-SM2 is a potent small-molecule SMN2 splicing enhancer used in spinal muscular atrophy (SMA) research. It is orally active and brain-penetrant, promotes U1-pre-mRNA association to increase exon 7 inclusion, and restores functional survival motor neuron (SMN) protein levels (reported EC50 ≈ 2 nM). Supplied as a high-purity solid and available in solution formats for experimental use.

  • Potent SMN2 splicing enhancer with low-nanomolar activity.
  • Orally active and brain-penetrant chemical probe.
  • Promotes exon 7 inclusion and increases SMN protein expression.
  • Supplied as a solid with high reported purity.
  • Available in multiple sizes and DMSO solution formats for flexibility.

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