O-Acetylsalicylic acid, 99%

Catalog No.	Quantity
AAA1248822	100 g
AAA1248836	500 g
AAA124880E	2500 g

Catalog No. AAA1248822 Supplier Thermo Scientific Chemicals Supplier No. A1248822

Description

CAS: 50-78-2 | C9H8O4 | 180.16 g/mol

O-Acetylsalicylic acid is the prototypical analgesic used in the treatment of mild to moderate pain. acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. Along with sodium salicylate (sc-3520), aspirin has been shown to block the long terminal repeat from the human immunodeficiency virus and the Ig κ enhancer from NFκB dependent transcription.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
O-Acetylsalicylic acid is the prototypical analgesic used in the treatment of mild to moderate pain. acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. Along with sodium salicylate (sc-3520), aspirin has been shown to block the long terminal repeat from the human immunodeficiency virus and the Ig κ enhancer from NFκB dependent transcription.

Solubility
Soluble in 100% ethanol (80mg/ml), DMSO (41mg/ml) or dimethyl formamide (30mg/ml); slightly soluble in Phosphate-buffered saline (PBS), pH 7.2 (2.7mg/ml).

Notes
Store at room temperature. Ensure good ventilation.

Specifications

Chemical Identifiers

• CAS: 50-78-2
• Molecular Formula: C9H8O4
• Molecular Weight (g/mol): 180.16
• MDL Number: MFCD00002430
• InChI Key: BSYNRYMUTXBXSQ-UHFFFAOYSA-N
• Synonym: aspirin, acetylsalicylic acid, 2-acetoxybenzoic acid, 2-acetyloxy benzoic acid, acetylsalicylate, o-acetylsalicylic acid, o-acetoxybenzoic acid, acylpyrin, polopiryna, easprin
• PubChem CID: 2244
• ChEBI: CHEBI:15365
• IUPAC Name: 2-acetyloxybenzoic acid
• SMILES: CC(=O)OC1=CC=CC=C1C(O)=O

• Melting Point: 133°C to 140°C
• Density: 1.4
• Flash Point: 250°C (482°F)
• Quantity: 100 g
• Beilstein: 779271
• Merck Index: 14,851
• Solubility Information: Soluble in 100% ethanol (80mg/ml),DMSO (41mg/ml) or dimethyl formamide (30mg/ml); slightly soluble in Phosphate-buffered saline (PBS),pH 7.2 (2.7mg/ml).
• Formula Weight: 180.15
• Percent Purity: 99%
• Chemical Name or Material: O-Acetylsalicylic acid

Safety and Handling

Hazard Category	H302-H500
Hazard Statement	GHS H Statement H302-H315-H319-H335 Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P264b-P270-P301+P312-P330-P501c
EINECSNumber	200-064-1
RTECSNumber	VO0700000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only