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BIOHIPPO O-GlcNAc Rabbit pAb
Supplier: BIOHIPPO BHA21821302
U-Blot Pan-O-GlcNAc Rabbit pAb is a Rabbit-derived polyclonal antibody that specifically recognizes O-GlcNAc a o-glcnacylation modification at Ser(S)/Thr(T) O-GlcNAc (short for O-linked -N-acetylglucosamine) is a reversible enzymatic post-translational modification found on serine and threonine residues of nucleocytoplasmic proteins The modification is characterized by a -glycosidic bond between the hydroxyl group of serine or threonine side chains and N-acetylglucosamine (GlcNAc) It is widely involved in the regulation of diverse cellular processes including transcription cell cycle signal transduction and stress response Dysregulation of O-GlcNAcylation has been closely linked to cancer neurodegeneration diabetes and inflammatory diseases Notably elevated O-GlcNAc levels in many cancers have been reported to suppress apoptosis by inhibiting caspase activation Supplied as 100 uL
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