O-(N-Succinimidyl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98+%, Thermo Scientific Chemicals

Description

Coupling reagent for peptide synthesis and the formation of other amides. Reactant for synthesis of liposomal contrast agents for magnetic resonance imaging, synthesis of protein labeling molecules, synthesis of thiol-reactive Cy5 derivatives.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Coupling reagent for peptide synthesis and the formation of other amides. Reactant for synthesis of liposomal contrast agents for magnetic resonance imaging, synthesis of protein labeling molecules, synthesis of thiol-reactive Cy5 derivatives.

Solubility
Soluble in acetonitrile 0.5 g/mL.

Notes
Moisture sensitive. Store under inert gas. Store away from oxidizing agents, water/ moisture.

Specifications

Chemical Identifiers

• CAS: 265651-18-1
• Molecular Formula: C9H16F6N3O3P
• Molecular Weight (g/mol): 359.21
• MDL Number: MFCD01863753
• InChI Key: STWZCCVNXFLDDD-UHFFFAOYSA-N
• Synonym: hstu, n,n,n',n'-tetramethyl-o-n-succinimidyl uronium hexafluorophosphate, o-n-succinimidyl-n,n,n',n'-tetramethyluronium hexafluorophosphate, hstu n,n,n',n'-tetramethyl-o-n-succinimidyl uronium hexafluorophosphate, dimethylamino 2,5-dioxopyrrolidin-1-yl oxy methylidene dimethylazanium hexafluorophosphate, ambotzrl-1039, o-n-succinimidyl-1,1,3,3-tetramethyluronium hexafluorophosphate, 2-succinimido-1,1,3,3-tetramethyluronim hexafluorophosphate, 2-succinimido-1,1,3,3-tetramethyluronium hexafluorophosphate, n,n,n',n'-tetramethyl-o-n-succinimidyl uroniumhexafluorophosphate
• PubChem CID: 16211151
• IUPAC Name: [dimethylamino-(2,5-dioxopyrrolidin-1-yl)oxymethylidene]-dimethylazanium;hexafluorophosphate
• SMILES: F[P-](F)(F)(F)(F)F.CN(C)C(ON1C(=O)CCC1=O)=[N+](C)C

• Melting Point: ∽220°C (decomposition)
• Quantity: 5 g
• Sensitivity: Moisture sensitive
• Solubility Information: Soluble in acetonitrile 0.5g/mL.
• Formula Weight: 359.21
• Percent Purity: ≥98%
• Chemical Name or Material: O-(N-Succinimidyl)-N,N,N',N'-tetramethyluronium hexafluorophosphate

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Store at -20°C; Store under Nitrogen

SDS

RUO – Research Use Only